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What Triggers Fibrosis in Scleroderma Skin?
What is your background, and what led you to focus your research on scleroderma?
During my PhD, I explored targeted treatments for a rare liver disease, driven by the desire to make a difference for patients. My interest in rare diseases and patient-centered research led me to join Professor Véronique Moulin’s team at LOEX, focusing on skin fibrosis in scleroderma. Today, I study this process to better understand the disease and improve care for those living with it. Here, I found both a scientific challenge and a human impact.
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What is your study about, and why might people with scleroderma be interested in it?
Skin fibrosis is often the first visible sign of scleroderma. In our study, we aim to understand how this process begins and what might trigger it. One clue we’re exploring is a molecule called Placental Growth Factor (PlGF), found at high levels in the blood of some patients. By recreating patients’ skin in the lab, we hope to uncover early drivers of fibrosis and identify new ways to protect both skin and internal organs.
What is one thing the scleroderma community does not know about you?
I love hiking and outdoor activities. I was terrified of moving to Quebec because of the winter. My friends couldn’t believe I’d survive since I sleep under a blanket even in summer! But here, it’s my favorite season. Last year, I even caught myself saying, “Oh, it’s warm today!” at –10°C.
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